P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT
- Product Name
- P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT
- CAS No.
- 75522-97-3
- Chemical Name
- P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT
- Synonyms
- AP5A;AP5A, LI3;AP5A, 3LI;A(5′)P5(5′)A trilithium salt;Diadenosine pentaphosphate (trilithium);P1,P5-DI(ADENOSINE-5'-PENTAPHOSPHATE), TRILITHIUM;P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT;P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT;Diadenosine pentaphosphate （as trilithium tetrahydrate）;P1,P5-Di(adenosine-5') pentaphosphate trilithium salt >=95%, powder
- CBNumber
- CB6278012
- Molecular Formula
- C20H26Li3N10O22P5
- Formula Weight
- 934.17
- MOL File
- 75522-97-3.mol
P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT Property
- storage temp.
- -20°C
- solubility
- H2O: soluble50mg/mL
- form
- powder
- color
- white to off-white
Safety
- WGK Germany
- 3
- HS Code
- 29349990
N-Bromosuccinimide Price
- Product number
- D6392
- Product name
- P1,P5-Di(adenosine-5′) pentaphosphate trilithium salt
- Purity
- ≥95%, powder
- Packaging
- 10mg
- Price
- $161
- Updated
- 2024/03/01
- Product number
- D6392
- Product name
- P1,P5-Di(adenosine-5′) pentaphosphate trilithium salt
- Purity
- ≥95%, powder
- Packaging
- 50mg
- Price
- $574
- Updated
- 2024/03/01
- Product number
- ND57347
- Product name
- P1,P5-Di(adenosine-5')pentaphosphate trilithium salt
- Packaging
- 250mg
- Price
- $600
- Updated
- 2021/12/16
- Product number
- ND57347
- Product name
- P1,P5-Di(adenosine-5')pentaphosphate trilithium salt
- Packaging
- 500mg
- Price
- $1000
- Updated
- 2021/12/16
- Product number
- ND57347
- Product name
- P1,P5-Di(adenosine-5')pentaphosphate trilithium salt
- Packaging
- 25mg
- Price
- $150
- Updated
- 2021/12/16
P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT Chemical Properties,Usage,Production
Chemical Properties
White powder
Uses
P1,P5-Di(adenosine-5′) pentaphosphate trilithium salt has been used as a adenylate kinase inhibitor and as a component of pre-AMPPNP rigor solution for treating muscle fibres.
Biochem/physiol Actions
A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5′-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In cardiac muscle, pM to nM concentrations significantly increase the open-probability of ryanodine-receptor (RyR2) gates, with prolonged action due to slow dissociation from the receptor.